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Detailed medicine guidance

Who can and cannot take sitagliptin

NHS medicines information on who can take sitagliptin and who may not be able to take it.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Who can take sitagliptin

Most adults aged 18 years and older can take sitagliptin.

Who may not be able to take sitagliptin

This medicine is not used to treat type 1 diabetes (when your body does not produce insulin).

Sitagliptin is not suitable for some people. To make sure it's safe for you, tell your doctor if you:

  • have ever had an allergic reaction to sitagliptin or any other medicine
  • have problems with your pancreas
  • have gallstones or very high levels of triglycerides (a type of fat) in your blood
  • are a heavy drinker or dependent on alcohol
  • have ever had any problems with your kidneys
  • are pregnant or breastfeeding, or trying to get pregnant

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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