Taking sitagliptin with other medicines and herbal supplements

Some medicines and sitagliptin can affect each other. Taking them at the same time as sitagliptin can cause low blood sugar or increase your risk of getting side effects.

Tell your doctor or pharmacist if you're taking:

• insulin or any other diabetes medicine – your doctor may want to lower the dose of these medicines when you start sitagliptin to reduce the risk of low blood sugar (hypoglycaemia)
• ketoconazole or itraconazole, medicines for fungal infections
• ritonavir, a medicine used to treat HIV and AIDS
• clarithromycin, an antibiotic for treating pneumonia and ear infections
• digoxin, a medicine for heart conditions, including heart failure

Make sure that your doctor and pharmacist know you're taking sitagliptin before starting or stopping any other medicine.

There's very little information about taking herbal remedies and supplements with sitagliptin. However, taking them at the same time as sitagliptin can cause low blood sugar.

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.