Need emergency help? Call 999 in United Kingdom.

Open local help

Detailed medicine guidance

Who can and cannot take letrozole

NHS medicines information on who can take letrozole and who may not be able to take it.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Who can take letrozole

Most adults aged 18 years old and over can take letrozole.

Who may not be able to take letrozole

Letrozole is not suitable for some people. Tell your doctor before starting to take this medicine if you:

  • have ever had an allergic reaction to letrozole or any other medicine
  • still have periods
  • are pregnant or breastfeeding
  • are trying to get pregnant – unless you are taking it as a fertility treatment
  • have serious kidney or liver disease
  • have been told you have fragile or brittle bones (osteoporosis)

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

More about Letrozole