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Detailed medicine guidance

Pregnancy, breastfeeding and fertility while taking letrozole

NHS medicines information on letrozole and whether you can take it while pregnant or breastfeeding.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Letrozole and pregnancy

Letrozole is not recommended when pregnant. This is because it affects your hormones and this can affect how your baby develops.

Talk to your doctor urgently if there is any chance that you could be pregnant.

Letrozole and breastfeeding

Letrozole is not recommended while you're breastfeeding.

There's no information on how letrozole passes into breast milk but it's likely to be a fairly high amount compared to most other medicines.

Letrozole affects hormones, which may affect how your baby develops.

Letrozole and fertility

Letrozole is sometimes used as a fertility treatment. Your fertility specialist will be able to answer any questions that you may have when it is being used for this purpose.

Meds New IA (H2) - Pregnancy non-urgent care card

Tell your doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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