Taking esomeprazole with other medicines and herbal supplements

When taken at the same time, some medicines can affect the way esomeprazole works. Esomeprazole can also affect the way other medicines work.

Taking them together can make you more likely to have side effects or stop one of the medicines working as well.

Tell your doctor if you're taking any of these medicines before you start taking esomeprazole:

• heart medicines such as digoxin
• cilostazol, a medicine that treats peripheral arterial disease
• antifungal medicines such as itraconazole, ketoconazole, posaconazole or voriconazole
• methotrexate, a medicine that treats psoriasis and rheumatoid arthritis
• HIV medicines
• phenytoin, an epilepsy medicine
• rifampicin, an antibiotic
• clopidogrel or warfarin, medicines to prevent or treat blood clots
• citalopram, diazepam, imipramine and other medicines used to treat anxiety and low mood

These are not all the medicines that may not mix well with esomeprazole. For a full list, see the leaflet inside your medicines packet.