This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
Varenicline does not usually have an effect on any other medicines. Check with your doctor before using varenicline with other stop smoking treatments.
However, when you stop smoking, with or without varenicline, your doctor may need to change your dose of medicines such as:
- theophylline or aminophylline, medicines for breathing problems
- erlotinib, a medicine to treat cancer
- riociguat, a medicine to treat high blood pressure in the lungs (pulmonary arterial hypertension)
- warfarin, a medicine to reduce blood clotting
- insulin, to treat diabetes
- olanzapine and clozapine, used to treat psychosis
View the original NHS website page ↗. Refreshed 19 August 2026.
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