Side effects of sulfasalazine

Side effects of sulfasalazine can vary depending on whether you're taking it as a tablet, suppository or liquid. Check the leaflet that comes with your medicine before taking or using it.

These common side effects happen in more than 1 in 100 people. There are things you can do to help cope with them:

It might help to take your sulfasalazine a few minutes before or after a meal.

If you need something to ease the discomfort, try taking an antacid. However, if you take an antacid, take it at least 2 hours before or at least 2 hours after you take sulfasalazine.

Stick to simple meals and do not eat rich or spicy food. It might help to take your sulfasalazine after you've eaten.

Drink lots of fluids, such as water or squash, to avoid dehydration. Speak to a pharmacist if you have signs of dehydration such as peeing less than usual or having dark strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.

If you take the combined contraceptive pill or the progestogen-only pill and you have severe, watery diarrhoea, or any diarrhoea that lasts for more than 24 hours, your contraception may not protect you from pregnancy. Check the pill packet for advice.

Stick to simple meals and do not eat rich or spicy food. It might help to take your sulfasalazine after you've eaten.

Drink plenty of fluids, such as water or squash, to avoid dehydration. Take small frequent sips if you're being sick. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee.

If you take the combined contraceptive pill or the progestogen-only pill and you're being sick, your contraception may not protect you from pregnancy. Check the pill packet for advice.

Try to rest and relax. It can help to eat and drink slowly and have smaller and more frequent meals. Putting a heat pad or covered hot water bottle on your stomach may also help. If you're in a lot of pain, speak to your pharmacist or doctor.

Sit down for a while until the feeling passes. Do not drive, cycle or use tools or machinery until you feel better.

Drink plenty of water and ask your pharmacist to recommend a painkiller. If the headache or pains continue or are severe, and taking a painkiller does not help, tell your doctor.

Try chewing sugar-free gum. If you're coughing try having frequent sips of water or other unsweetened drinks.

Avoid having a big meal, smoking, or drinking alcohol, tea or coffee in the evening. Try not to watch television or use your mobile phone before going to bed. Instead, try to relax for an hour before bedtime.

Speak to your doctor if this does not go away or lasts longer than 2 days.