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Detailed medicine guidance

Taking solifenacin with other medicines and herbal supplements

NHS medicines information on possible interactions with solifenacin and other medicines, herbal remedies and supplements.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Cautions with other medicines

Some medicines and solifenacin can affect each other. This can increase the chance of side effects.

Tell your pharmacist or doctor if you're taking:

  • any medicine that makes you drowsy, gives you a dry mouth, or makes it difficult for you to pee – taking solifenacin might make these side effects worse
  • itraconazole, a medicine used to treat fungal infections
  • ritonavir, a medicine used to treat HIV

Taking solifenacin with painkillers

It's safe to take solifenacin with everyday painkillers like paracetamol and ibuprofen.

View the original NHS website page ↗. Refreshed 19 August 2026.

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