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Detailed medicine guidance

Taking pregabalin with other medicines and herbal supplements

NHS medicines information on possible interactions with pregabalin and other medicines, herbal remedies and supplements.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Cautions with other medicines

It's usually safe to take pregabalin with other medicines.

For safety, tell your doctor before you start taking pregabalin if you're taking:

  • strong opioid painkillers such as morphine, codeine or oxycodone
  • medicines that make you feel sleepy or dizzy – pregabalin can make these side effects worse

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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