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Detailed medicine guidance

Who can and cannot take Pepto-Bismol

NHS medicines information on who can take Pepto-Bismol and who may not be able to take it.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Who can take Pepto-Bismol

Most adults and young people aged 16 years and over can take Pepto-Bismol.

Who may not be able to take Pepto-Bismol

Do not take this medicine if you are pregnant or breastfeeding.

Pepto-Bismol is not suitable for some people. To make sure this medicine is safe for you, tell your doctor or pharmacist if you have:

  • ever had an allergic reaction to bismuth subsalicylate or any of the other ingredients in Pepto-Bismol or Pepti Calm
  • ever had an allergic reaction to aspirin or any other medicine
  • diabetes
  • gout
  • a rare inherited condition called phenylketonuria where you cannot have aspartame – the chewable tablets contain aspartame
  • have a blood clotting disorder

Pepto-Bismol liquid and tablets both contain a colouring called amaranth. Some people can have an allergic reaction to amaranth.

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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