This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Common side effects of nortriptyline
These side effects can sometimes happen if you take nortriptyline. There are things you can do to help cope with them:
Constipation
Get more fibre into your diet such as fresh fruit, vegetables and cereals. Try to drink several glasses of water or squash every day. If you can, it may also help to increase your level of exercise.
Feeling dizzy
This may be due to low blood pressure. Drink plenty of water or squash. Do not stand up too quickly after you've been sitting or lying down. Do not drive, cycle or use tools or machinery until this feeling passes. It's best not to drink alcohol until you see how the medicine affects you.
Dry mouth
Chew sugar-free gum or have some sugar-free sweets.
Feeling sleepy
Take nortriptyline in the evening. It's best not to drink alcohol until you see how the medicine affects you. Do not drive, cycle or use tools or machinery while you're feeling sleepy.
Difficulty peeing
Try to relax when you pee. Do not try to force the flow of pee. If you cannot pee, try again a short time later.
Call 111 or talk to your doctor GP urgently if you cannot pee at all.
Headaches
Make sure you rest and drink plenty of fluids. It's best not to drink alcohol until you see how the medicine affects you. Try taking paracetamol or ibuprofen if you need pain relief. Talk to your doctor if the headaches do not go away or are severe.
Keep taking the medicine but talk to your doctor or pharmacist if the advice on how to cope does not help and these side effects bother you or do not go away.
View the original NHS website page ↗. Refreshed 19 August 2026.
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