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Detailed medicine guidance

Who can and cannot take nefopam

NHS medicines information on who can take nefopam and who may not be able to take it.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Who can take nefopam

Most adults can take nefopam.

Who may not be able to take nefopam

Do not take nefopam for pain caused by a heart attack.

Do not take nefopam if you:

  • have ever had an allergic reaction to nefopam or any other medicine
  • have epilepsy, or have ever had a seizure or fit

Nefopam is not suitable for some people. To make sure it's safe for you, tell your doctor if you:

  • have liver or kidney problems
  • have ever had difficulty peeing
  • have an uncommon kind of glaucoma (increased pressure in the eye) called angle closure glaucoma
  • are trying to get pregnant, are already pregnant or breastfeeding

View the original NHS website page ↗. Refreshed 19 August 2026.

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