This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
Some medicines can affect the way methylphenidate works and increase the risk of side effects.
Talk to their doctor or a pharmacist before giving them methylphenidate if your child is taking any other medicines, including:
- medicines to treat depression or other mental health conditions
- medicines for epilepsy
- blood pressure medicines
- medicines that treat or prevent blood clots
- medicines for coughs and colds
Some cough and cold medicines can affect blood pressure so speak to a pharmacist or doctor before buying these for your child. It's important to check if they're OK to have while taking methylphenidate.
These are not all the medicines that may cause problems if your child takes them with methylphenidate. For a full list, see the leaflet inside the medicine packet.
View the original NHS website page ↗. Refreshed 19 August 2026.
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