Who can and cannot take methotrexate

Most adults and children can take methotrexate.

Methotrexate is not suitable for some people. To make sure it's safe for you, tell your doctor before taking it if you:

• have ever had an allergic reaction to methotrexate or any other medicine
• are pregnant, trying to get pregnant or are breastfeeding
• have severe liver or kidney disease, or a blood disorder
• have an infection
• have mouth ulcers, or have been diagnosed with a stomach ulcer or duodenal ulcer
• are due to have a live vaccine (this includes the live flu vaccine usually given to children)

You may have a chest X-ray and a breathing test to check your lungs before starting treatment. These tests will help show your doctor whether methotrexate is suitable for you.