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Detailed medicine guidance

Who can and cannot take mesalazine

NHS medicines information on who can take mesalazine and who may not be able to take it.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Who can take mesalazine

Most adults and children aged 5 years old and older over can take mesalazine.

Who may not be able to take or use mesalazine

Although most adults and children aged 5 years old and older over can take mesalazine, it may not be suitable for some people. To make sure it's safe for you, tell a doctor before taking if you:

  • have ever had an allergic reaction to mesalazine, aspirin, or any other medicines like it, such as methylsalicylate or choline salicylate
  • have ever had an allergic reaction to any other medicine
  • have ever had kidney problems while taking other medicines such as sulfasalazine
  • have ever developed a severe skin rash, skin peeling, blistering or mouth sores after using mesalazine
  • have problems with your kidneys or liver
  • are trying to get pregnant, already pregnant, or breastfeeding

View the original NHS website page ↗. Refreshed 19 August 2026.

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