This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Cautions with other medicines
There are many medicines that can affect the way hydrocortisone tablets work.
It's important to ask your doctor or pharmacist if a medicine is safe to take with hydrocortisone tablets before you start taking them. This includes prescription medicines and ones that you buy such as ibuprofen.
Mixing hydrocortisone tablets with herbal remedies and supplementsThere's not enough information to say that complementary medicines and herbal remedies are safe to take with hydrocortisone. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
Meds New IA (H2) - Cautions with other medicines alert
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.
View the original NHS website page ↗. Refreshed 19 August 2026.
Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.