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Detailed medicine guidance

Having hydrocortisone injections with other medicines and herbal supplements

NHS medicines information on possible interactions with hydrocortisone injections and other medicines, herbal remedies and supplements.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Cautions with other medicines

Some medicines can affect how hydrocortisone injections work and can increase the risk of side effects.

Tell your doctor or pharmacist if you're using any other medicines before having a hydrocortisone injection. This includes prescription medicines and ones that you buy like ibuprofen and aspirin.

Mixing hydrocortisone injections with herbal remedies and supplements

There's not enough information to say that complementary medicines and herbal remedies are safe to take if you're having hydrocortisone injections. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Meds New IA (H2) - Cautions with other medicines alert

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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