This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Serious side effects of cyanocobalamin
As cyanocobalamin contains cobalt, it can cause sensitivity reactions in people who have an allergy to cobalt. Symptoms can start straight away or up to 3 days after having a dose.
Talk to your doctor or call 111 if you get an allergic skin reaction such as a rash or hives.
View the original NHS website page ↗. Refreshed 19 August 2026.
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