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Side effects of cyanocobalamin

NHS medicines information on side effects of cyanocobalamin and what you can do to cope.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Serious side effects of cyanocobalamin

As cyanocobalamin contains cobalt, it can cause sensitivity reactions in people who have an allergy to cobalt. Symptoms can start straight away or up to 3 days after having a dose.

Talk to your doctor or call 111 if you get an allergic skin reaction such as a rash or hives.

View the original NHS website page ↗. Refreshed 19 August 2026.

Licensed under the Open Government Licence v3.0 ↗. MyPHU is independent and is not endorsed by the NHS.

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