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Detailed medicine guidance

Pregnancy, breastfeeding and fertility while taking co-dydramol

NHS medicines information on co-dydramol and whether you can take it while pregnant or breastfeeding.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Co-dydramol and pregnancy

You can take co-dydramol in pregnancy if you need to.

Co-dydramol contains paracetamol and dihydrocodeine. Although paracetamol is safe to take at any time in pregnancy, taking dihydrocodeine towards the end of pregnancy may cause your baby to have withdrawal symptoms, such as drowsiness, after they're born. Your baby may need extra time in hospital for observation.

It's important to treat pain in pregnancy. Co-dydramol might sometimes be the best option for pain during pregnancy, but speak to your doctor. They can help you decide what's right for you and your baby.

Co-dydramol and breastfeeding

If your doctor or midwife says your baby is healthy, it's usually OK to take co-dydramol while breastfeeding. However, only take it if your doctor advises you to. Try to take it in low doses and only use it for a short time.

It's usually better to take paracetamol on its own while breastfeeding.

Co-dydramol contains paracetamol and dihydrocodeine. Paracetamol gets into breast milk in small amounts. It's not known how much dihydrocodeine gets into breast milk, but it's also thought to be a small amount. It's unlikely that co-dydramol will cause any side effects in your baby.

Talk to your doctor, pharmacist, midwife, or health visitor if you have any concerns about your baby while you are breastfeeding. This includes if your baby:

  • is not feeding as well as usual
  • has constipation

Call 111 for advice or go to A&E now if:

  • your baby is unusually sleepy
  • your baby has breathing problems

However, these effects are very rare, and unlikely to happen, especially with low strength co-dydramol taken for a short time.

Co-dydramol and fertility

Taking co-dydramol that contains higher levels of dihydrocodeine, for a long time, can make it more difficult for you to get pregnant or to make someone pregnant. This is because dihydrocodeine can cause hypogonadism (where the body stops making enough sex hormones).

When you stop taking co-dydramol, your sex hormones should go back to normal.

If you're worried about co-dydramol and your fertility, talk to your doctor.

Meds New IA (H2) - Pregnancy non-urgent care card

Tell your doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding

View the original NHS website page ↗. Refreshed 19 August 2026.

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