This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.
Common side effects of chlorhexidine sore throat and dental treatments
Some people get peeling skin inside their mouth when using chlorhexidine. If this happens to you, stop using the medicine and the side effect will usually clear up. Speak to your dentist or doctor, who may be able to recommend a different medicine.
These common side effects of chlorhexidine sore throat and dental treatments happen in more than 1 in 100 people. They're usually mild and do not last long. There are things you can do to help cope with them:
Dry mouth
Have sips of water. Try chewing sugar-free gum or sucking sugar-free sweets. If this still bothers you, talk to your doctor, pharmacist or practice nurse. They may be able to recommend a spray, gel or lozenges to keep your mouth moist.
Short bursts of a mild burning, tingling or strange taste in your mouth
This sometimes happens when you first start treatment but improves as you keep using chlorhexidine. If it does not go away, talk to your doctor or pharmacist about it. It may be an allergy.
Your tongue changes colour
This is not permanent and will go when you stop using chlorhexidine.
Stained teeth
This is not permanent and will go when you stop using chlorhexidine. Make sure you brush your teeth regularly.
Speak to a doctor, dentist or pharmacist if the advice on how to cope does not help and a side effect is still bothering you or does not go away.
View the original NHS website page ↗. Refreshed 19 August 2026.
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