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Detailed medicine guidance

Taking bendroflumethiazide with other medicines and herbal remedies

NHS medicines information on possible interactions with bendroflumethiazide and other medicines, herbal remedies and supplements.

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Cautions with other medicines

Some medicines can affect the way bendroflumethiazide works and increase the chances of you having side effects.

Tell your doctor or pharmacist before starting to take bendroflumethiazide if you take any other medicines, including:

  • other medicines that lower blood pressure
  • allopurinol, a medicine to treat gout
  • non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, or aspirin for pain relief
  • insulin or any other medicine used to treat diabetes
  • ciclosporin, a medicine used for preventing transplant rejection or to treat other medical conditions such as psoriasis or rheumatoid arthritis
  • medicines used to treat heart problems, such as amiodarone, digoxin, disopyramide, flecainide or sotalol
  • medicines to treat sickness or nausea (antiemetics), such as domperidone, metoclopramide or prochlorperazine
  • certain antidepressants, such as amitriptyline, citalopram or venlafaxine
  • medicines for other mental health problems, such as chlorpromazine, pimozide or trifluoperazine
  • other diuretics (medicines that help your body get rid of extra fluid)
  • steroids, such as prednisolone or hydrocortisone
  • some medicines used for asthma, including inhalers such as formoterol, salbutamol or salmeterol
  • carbamazepine, a medicine for epilepsy
  • medicines to treat calcium or vitamin D deficiency, including alfacalcidol or calcitriol

These are not all the medicines that may cause problems if you take them with bendroflumethiazide. For a full list, see the leaflet inside your medicine packet.

Taking bendroflumethiazide with everyday painkillers

Some painkillers, especially ones that dissolve in water (soluble), can contain a lot of sodium, which is found in salt. Too much sodium can stop medicines for high blood pressure working properly.

Medicines that contain a lot of sodium include:

Speak to a pharmacist or doctor to find out if these medicines are safe for you to take with bendroflumethiazide.

View the original NHS website page ↗. Refreshed 19 August 2026.

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