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Medicine guide

Docusate

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Docusate

What it's for

Docusate

How it's used (previously Dosage and administration)

Docusate

Side effects

Docusate

Who it's for

Docusate

Interactions

Docusate is a type of medicine called a stool softener. It's used to treat constipation (difficulty pooing).

Docusate comes as capsules or a liquid you swallow, or a gel you put in your bottom (enema). Follow the instructions that come with your medicine.

Side effects of docusate include feeling sick (nausea), stomach cramps or discomfort, and diarrhoea. More serious side effects are rare.

Docusate is suitable for most adults and children aged 6 months and over, but always check before taking it because it's not suitable for everyone.

Taking docusate with some medicines, remedies or supplements may cause problems. Always check before taking it.

What docusate is for

Docusate can be used:

  • to treat constipation (difficulty pooing), such as not pooing very often or having poo that's dry and hard
  • if you have a condition when it helps if your poo is soft or you can poo more easily, like piles or an anal fissure
  • to empty your bowel before some tests or procedures

Docusate is a type of laxative called a stool softener. Stool softeners work by allowing more water into your poo. This makes the poo softer and easier to push out.

It may also help trigger the muscles in your bowel to move poo along.

Docusate also comes as ear drops used to help soften and remove ear wax.

How to take docusate

Docusate comes as capsules or a liquid (oral solution) that you swallow, and as a gel that you put in your bottom (enema).

It usually starts to work within 1 to 2 days if you're swallowing it. It works more quickly if you use an enema, usually within 20 minutes.

How much you need to take and for how long depends on why you're taking it. Always follow the advice your doctor or pharmacist gives you.

Drink plenty of fluids to stay hydrated if you're taking docusate capsules or liquid for constipation.

How to take or use different types of docusate

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Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.

Important

See a doctor for advice if you've taken docusate capsules or liquid for more than a few days and your symptoms have not improved or have got worse.

If you miss a dose of docusate

If forget to take a dose of docusate, take it as soon as you remember unless it's nearly time for your next dose.

If it is nearly time for your next dose, skip the dose you missed and take your next dose at the usual time.

Do not take 2 doses to make up for a missed one.

If you take too much docusate

Taking an extra dose of docusate is unlikely to cause problems, but it's important to get medical advice if you take too much and feel unwell.

Speak to a pharmacist as soon as possible if:

  • you've taken more docusate than it says on the packet, leaflet or prescription and have symptoms such as being sick (vomiting), diarrhoea or bloating, or you feel dizzy and weak

If you're unable to speak to a pharmacist or you took too much of your medicine on purpose, call NHS 111 for advice.

Find a pharmacy

Side effects of docusate

Like all medicines, docusate can cause side effects, although not everyone gets them.

Common side effects

  • diarrhoea
  • stomach cramps
  • feeling sick (nausea)
  • a burning feeling in your mouth or throat, if you're using the liquid medicine – drinking water after taking it can help
  • soreness or irritation around your bottom, if you're using an enema

Speak to a pharmacist or doctor if:

  • you have any side effects that bother you or do not go away

They may be able to give you advice about how to reduce any side effects or may suggest reducing your dose.

Find a pharmacy

Serious side effects

Docusate can sometimes cause serious side effects, although most of them are rare.

Possible serious side effects of docusate include:

  • a serious allergic reaction (anaphylaxis) – causing symptoms such as a swollen throat or tongue, a raised itchy rash and difficulty breathing
  • low potassium in your blood – causing symptoms such as muscle weakness, tiredness, needing to pee a lot and heart rhythm problems (this can happen if you have frequent diarrhoea from taking docusate for a long time)

Call 999 if:

  • you're taking docusate and think you might be having anaphylaxis

If you think you're having any other serious side effect, call NHS 111.

Who can and cannot take docusate

Most adults and children aged 6 months and over can take docusate.

But docusate is not suitable for everyone. For example, it may not be suitable if:

  • you have ever had an allergic reaction or serious side effect from docusate or another laxative
  • you have stomach pain without a cause
  • you feel sick or have been sick in the last 24 hours
  • you have a blockage in your bowel that is not from constipation
  • you're using a docusate enema and have inflammatory bowel disease, such as Crohn's disease or ulcerative colitis

Do not use a docusate enema if you have piles (haemorrhoids), bleeding, sores or tears around your bottom.

Check the packet or leaflet that comes with your medicine to see if it's suitable for you or your child. Speak to a pharmacist or doctor if you're not sure if you can take it.

Breastfeeding and docusate

Docusate can usually be used while breastfeeding.

It's rare for breastfed babies to get any side effects from medicine you're taking, but speak to a healthcare professional if you have any concerns about your baby.

Pregnancy and docusate

You can usually take docusate if you're pregnant, but it's best to speak to a pharmacist or doctor first.

Taking docusate with other medicines, food and drink

There are some medicines, remedies and supplements that may not mix well with docusate.

Speak to a doctor of pharmacist if you're also taking another laxative, such as senna. They may suggest you change your dose.

Before you take docusate, check the packet or leaflet that comes with the medicine to see if it's suitable for you. Speak to a pharmacist or doctor if you're not sure if you can take it.

Food, drink and alcohol with docusate

You can eat and drink as normal when taking docusate.

Drink plenty of fluids while taking docusate for constipation. This helps stop constipation getting worse.

Content supplied by the NHS website

Content supplied by the NHS website, refreshed 26 October 2026. View the original NHS article ↗

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