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Medicine guide

Clonazepam

About this information

This NHS content is written for people in England. Medicine names, availability, prescribing and services may differ in other countries.

Clonazepam

What it's for

Clonazepam

How it's used (previously Dosage and administration)

Clonazepam

Side effects

Clonazepam

Who it's for

Clonazepam

Interactions

Clonazepam is a type of medicine called a benzodiazepine. It's mainly used to treat epilepsy and sometimes panic disorder.

Clonazepam usually comes as tablets or a liquid you swallow. Follow the instructions that come with your medicine.

Side effects of clonazepam include muscle weakness, and feeling low, sleepy and dizzy. More serious side effects are rare.

Clonazepam is suitable for most adults and children, but always check before taking it because it's not suitable for everyone.

Taking clonazepam with other medicines, such as opioid painkillers, can cause problems. Always check before taking it.

What clonazepam is for

Clonazepam is a type of medicine called a benzodiazepine. It's used to used to treat seizures caused by epilepsy.

It's also sometimes used for panic disorder when other medicines have not worked.

It works by calming activity in your brain and nerves. For epilepsy, this helps to reduce the number of seizures you have and can make seizures less serious.

How to take clonazepam

How much clonazepam you need to take depends on your age and why you're taking it.

For epilepsy, you usually take it once a day, in the evening. But some people may need to take it in divided doses.

Your doctor will usually prescribe a low dose when you first start taking clonazepam and increase it if needed.

When taking clonazepam:

  • swallow tablets whole with water
  • use the syringe or spoon that comes with the liquid medicine to help you measure the right dose
  • you can take it with or without food

Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.

If you miss a dose of clonazepam

If you forget to take a dose, skip the missed dose and take your next dose at the usual time.

Do not take 2 doses to make up for a missed dose.

If you take too much clonazepam

Taking an extra dose of clonazepam can be dangerous.

Call NHS 111 if:

  • you've taken more than your prescribed dose of clonazepam

Information

If you're told to go to A&E, do not drive. Ask someone to drive you or call 999 and ask for an ambulance.

Bring the clonazepam packet or leaflet inside it, any remaining medicine, and any other medicines you take.

How to stop taking clonazepam

Do not stop taking clonazepam unless your doctor tells you to. Stopping suddenly can cause withdrawal symptoms and may make your epilepsy symptoms worse.

If you need to stop taking clonazepam, your doctor will usually reduce your dose slowly over several weeks or months.

It's possible to become addicted to clonazepam. Your doctor will prescribe the lowest dose you need to help your symptoms.

Talk to your doctor if you're worried about addiction or stopping taking clonazepam.

Always follow your doctor's advice.

Side effects of clonazepam

Like all medicines, clonazepam can cause side effects, although not everyone gets them.

Possible side effects of clonazepam include:

  • feeling sleepy, tired, dizzy or less alert
  • headaches
  • feeling restless or agitated
  • feeling low or depressed
  • shaking
  • muscle weakness

If you feel sleepy, dizzy or less alert after taking clonazepam, do not drive, ride a bike or use machinery until you no longer have these symptoms.

Speak to a pharmacist or doctor if:

  • you have any side effects that bother you or do not go away

They may be able to give you advice about how you can reduce the side effects. Keep taking your medicine unless you're advised to stop.

Find a pharmacy

Serious side effects

Clonazepam can sometimes cause serious side effects, although most of them are rare.

Possible serious side effects of clonazepam include:

  • an allergic reaction (anaphylaxis) – causing symptoms such as a swollen throat or tongue, a raised, itchy rash or difficulty breathing
  • difficulty breathing – causing slower, more shallow breaths or very slow breathing
  • liver problems – causing symptoms such as darker pee than normal, pale poo, and yellowing of the whites of your eyes or skin (yellowed skin may be more difficult to see on black or brown skin)
  • mental health problems – such as hearing or seeing things that are not there (hallucinations), believing things that are not true (delusions), feeling low or depressed, or having thoughts of suicide or harming yourself

Call 999 if:

  • you're taking clonazepam and have severe difficulty breathing or think you might be having anaphylaxis

If you're having thoughts of harming yourself, or think you're having any other serious side effect, call NHS 111.

Who can and cannot take clonazepam

Most adults and children can take clonazepam.

But it's not suitable for everyone. For example, it may not be suitable if:

  • you've had an allergic reaction or other serious side effect from clonazepam or another benzodiazepine
  • you have sleep apnoea or breathing problems
  • you have muscle weakness or a condition that causes it, such as myasthenia gravis
  • you have kidney or liver problems
  • you've been addicted to alcohol, drugs or prescription medicine before, especially opioids
  • you have ever had depression or thoughts of harming yourself
  • you have porphyria, a rare blood condition

Before taking clonazepam, tell your doctor if you have any medical conditions.

Breastfeeding and clonazepam

Tell your doctor if you're breastfeeding.

Clonazepam is sometimes used while breastfeeding, but only if the benefits outweigh the risks.

It's possible for breastfed babies to get side effects if you're taking clonazepam, such as being sleepier or breathing more slowly than usual. Speak to a healthcare professional or call NHS 111 if you have any concerns about your baby.

Do not sleep in the same bed (co-sleep) with your baby if you've taken clonazepam or any other medicine that makes you sleepy or drowsy, as it can increase the risk of sudden infant death syndrome (SIDS).

Pregnancy and clonazepam

Tell your doctor if you're pregnant, or get pregnant while taking clonazepam.

Clonazepam may be used during pregnancy. Your doctor will talk to you about the risks and benefits of taking it while you're pregnant.

You may also be advised to give birth in hospital so you and your baby can be closely monitored after you've given birth.

Taking clonazepam with other medicines, food and drink

There are some medicines, remedies and supplements that may not mix well with clonazepam.

This includes:

  • other medicines for epilepsy, such as carbamazepine, lamotrigine and sodium valproate
  • medicines for moderate or severe pain, including opioid painkillers like morphine, codeine or oxycodone
  • medicines for sleep or anxiety problems
  • some medicines for mental health problems, such as antidepressants or antipsychotics
  • cimetidine, used to lower the amount of acid in your stomach
  • rifampicin, an antibiotic

Before taking clonazepam, tell your doctor if you're taking any other medicines, herbal remedies, vitamins or supplements.

Food, drink and alcohol with clonazepam

Do not drink alcohol while taking clonazepam. Alcohol can increase the effects of the medicine, which can cause breathing problems and make it very difficult to wake up.

Otherwise, you can eat and drink as normal while taking clonazepam.

Content supplied by the NHS website

Content supplied by the NHS website, refreshed 26 October 2026. View the original NHS article ↗

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